The scientific studies on drug delivery systems that transport drugs to the targeted tissues, at a certain rate and desired time intervals, have gained popularity. The main goal of the drug delivery and release systems is to maintain the drug level in the blood plasma by balancing the amount of active ingredient. In this study, pH and temperature sensitive drug carriers were prepared using chitosan as a biopolymer and clay as a natural material. The characterization of the prepared materials was performed for structural analysis by FT-IR and for morphological analysis by SEM instruments. The swelling properties of the prepared materials were investigated. In this work, Ranitidine-HCl was used as a model drug. The prepared drug carriers were first loaded with Ranitidine-HCl and release properties of the materials were investigated at two different temperatures (25oC, 37oC) and various pH medium. The data obtained from the experiments indicated that the maximum release of Ranitidine–HCl from the prepared sample was observed at pH=7,6 buffer solution at both temperatures by comparing buffer solutions. It has been shown that the materials prepared in this study are suitable carriers for the Ranitidine-HCl drug active ingredient.

Every organization is made up of employees who can be its great strength but also a weakness, and the results, quality of work and achievement of organizational goals are largely determined by the behavior of the people who make it up. One of the key factors that influence the behavior of people in general, as well as the behavior in the work organization and attitude towards work are motives. Starting from the fact that human behavior is driven by different motives, that different people have different structure of motives and needs, the aim of this research is aimed at conducting the segmentation of employees in selected businesses in Bosnia and Herzegovina, engaged in different types of activities and of different structures of equity, according to socio-demographic factors – gender, age of respondents, years of service, marital status, type of education, the amount of monthly income of employees and the amount of family monthly income of employees. Also, the goal is to determine whether there are significant differences in the motives of individual groups (segments) of employees and how such indicators can contribute to the creation of an adequate motivational strategy within the work organization

It is the fact that sexual deviations and delicts are present in all cultures and within all peoples during the whole history of mankind and this have always caused the attention of theoreticians in their quest for its roots. Having on mind this fact, we have analysed the family dynamics during early childhood of sexual delinquents through the search for the differences in perceived parental acceptance or rejection, family affective attachment and accepted script injunctions – in relation to healthy examinees. The research is based on sample of 42 examinees categorised in two groups: a group of sexual delinquents and a group of examinees from general population without psychological disorder diagnosis. The analyses of perceived index of parental acceptance is carried out by Rohner PAR-Q questionnaire, for the determination of affective attachment patterns we use modified Brennan questionnaire for the estimation of family affective attachment, while level and the nature of acquired script injunctions have been asnalysed by the Scale of script injunctions. The results show that there are statistically significant differences between the two groups regarding dominating patterns of family affective attachment with more dominant insecure attachment in the group of sexual offenders. Too, one of the characteristics of this group is above average exposure to the existence injunction, value injunction, Don`t be a child injunction, and health injunction, while differences regarding perceived index of parental acceptance/rejection are not statistically significant

The aim of this paper is to get acquainted with the process of integration of Bosnia and Herzegovina into the European Union. On May 26, 1999, the Commission presented a proposal to initiate the so-called Stabilization and Association Process. This was approved at the meeting of the Council of the European Union in Luxembourg on June 21, 1999. The Stabilization and Association Process was formalized at the Zagreb Summit in 2000, at which the Union reaffirmed its desire to contribute to the consolidation of democracy and to give decisive support to the process of reconciliation and cooperation between the countries of the Western Balkans. The term Western Balkans is political and is used to distinguish this group of countries from previous ones that have already established relations with the European Union. Methods of analysis, synthesis, induction, deduction, abstraction, description, compilation and content analysis were used in the research. The research shows that Bosnia and Herzegovina still does not sufficiently meet the criteria relating to the stability of institutions guaranteeing democracy, the rule of law, human rights and respect for and protection of minorities, set by the Copenhagen European Council in 1993. Bosnia and Herzegovina must align its constitutional framework with European standards and ensure the functionality of its institutions in order to be able to take on the Union’s obligations. In this regard, it is necessary to reform the institutions so that they can effectively participate in decisionmaking at EU level and implement and enforce the acquis.

Radio survives despite the opinion that it is an outdated medium that is rapidly losing its audience. It is forgotten that radio is still a medium that addresses the widest layer of the audience. The fact that the audience pays attention and time to the Internet leaves only additional space for the development of increasingly popular forms of web radio that appeal to the younger generations. The radio journalist has changed his status and is becoming multidimensional, ready to go to the field, record, edit and address the audience. Radio may have lost its original form but with its convergent abilities it has a new chance to become among the media of first choice because young people in their loneliness increasingly appreciate intimacy, someone’s imaginary presence and the warmth of a voice. We will especially analyze radio area in Bosnia and Herzegovina which is still awaiting the implementation of radio digitalization in order to keep pace with changes in the world and the environment. During that time, it is necessary to provide all the preconditions for overcoming technological limitations.

The principle of separation of powers is one of the basic pillars of the rule of law, and its essence is to prevent abuse of power because the division of power does not exclude the possibility of intertwining competencies of different holders of state power. Precisely because of this, no matter in what form the division of power is realized, conflicts between different holders of power and encroachment on the competence of other holders of power are inevitable. Disputes about conflicts of jurisdiction arise under the influence of various factors, the most important of which is certainly the form of state organization, ie the degree of territorial decentralization and the way in which the division of power at the vertical level was achieved. Any form of decentralization, be it federal units, territorial autonomy or local self-government units, is necessarily a source of potential conflicts between central and non-central government. Therefore, the basic issue that arises in any form of decentralized state, and especially the federal one, is precisely the issue of the relationship between central and noncentral government. The paper pays special attention to Bosnia and Herzegovina, ie the issue of distribution of competencies as a factor of competition disputes and the role of the Constitutional Court in resolving these disputes and establishing clear boundaries between different holders of state power in the vertical.

The paper aims to review the digital evolution process in the Georgian economy and to evaluate potential gaps relative to other countries. Digital evolution is a multidimensional concept, therefore to underline the key sectors where the digital divide is substantial between the developed world and Georgia is essential for further, more specific research. The research’s major expected outcome serves to fill the local academic literature gap related to digital development’s role in the digital economy, therefore it can be a basis for upcoming research in this field in Georgia. This approach can be also used for other developing countries which are transforming to digital economies. It is answering the specific questions: Is there a digital gap between Georgia and other economies? And, which digital sectors are the most or least developed? Digital development is influenced by several factors. The research uses digital evolution indices to measure digital evolution in different sectors from demand conditions to institutional ecosystems.

A modern marketing system is based on supply, market conditions and regulated institutions. Defined as a pillar of the rule of law, the authority and strength of institutions depends on political stability, legal solutions and the rule of law, efficiency of the public administration system, corruption, civil liberties, but also commitment to philosophy and marketing concepts. Unfortunately, Bosnia and Herzegovina has not yet established an appropriate system in any of these areas and it is obvious that there is a significant gap between the situation in this area in our country and in the developed world. The rules according to which the socioeconomic structure is regulated, as well as the institutions and related institutions, do not form a system that, in accordance with modern principles of developed economies, provides efficiency and support for economic activities, and contributes more strongly to the goals of modern and democratic socio-political system. Marketing, with the philosophy of its approach, strongly determines economic and social trends, so that the developed marketing concept in the institutions of the system is one of the conditions for stability and progress of the country. The aim of this research is to point out that marketing in the security structures of Bosnia and Herzegovina is small and insufficient, that it is not at the level that provides the best in the society and shows us the outcome of such a situation for security and development processes in the community.

We understand circular economy as an economic system that aims to eliminate waste throughout an entire value chain – including manufacturing, production and use. Circular economy is also a way of rethinking our approach to waste and to every single stage of a products´ life cycle. Slovakia has been challenged recently to keep up with the changes the automotive industry is undergoing, including the green and digital transformation. The automotive industry producers have to accelerate innovations based on the required transition towards circular economy, an alternative to the unsustainable linear model of economy. The paper focuses on the principles of circular economy, demonstrated by the example of the Slovak automotive industry. The aim of this paper is to evaluate the current state of use of circular economy aspects in the automotive industry in Slovakia. We found out practical approaches of circular economy incorporated by Slovak automotive producers. In context of circular economy, Slovakia perceives prospective transition to automotive electrics industry, the introduction of new progressive technologies and sophisticated production. 

In all areas of society, it is necessary to actively and continuously act on unique (constitutive) rules that apply equally to all and perform non-selective and unprivileged regulation, coordination, organization and limitation of human behavior. These are institutions that can best present their functions. Economics has clearly shown how the real (and even virtual) economic reality works in principle and determined that the role of institutions in society and economy is not only necessary and unavoidable, but also a priority, as a metabasis and meta-mechanism. This paper presents a study of the impact of constitutional (political) rules, economic rules and contracts on the construction of socio-cultural capital. The aim of the research is to prove that all development models that have ignored institutions have proved unsustainable. The constitution has the role of preventing arbitrariness, ie “rule without rules”.

Managing the efficiency of a company and, in connection with that, the choice of the way of measuring efficiency is becoming more and more important, especially in the conditions of a modern business environment characterized by complexity, dynamism, uncertainty and heterogeneity. The company, in addition to being in different business environments, also has its own specifics, so the question arises what it means for a particular company to be efficient and what is an adequate model for measuring the efficiency of that company. In general, a good efficiency measurement system involves a set of performance measures, that is, a metric that quantifies efficiency and effectiveness. The paper presents a review of traditional and new integrated models for measuring the performance of enterprises in the function of control.

Development of information technologies has taken revolution in automation technology. The use of new telecommunication technologies makes possible observing diagnostic parameters from distance and to undertake maintenance activities based on result of observation. In this way is possible to eliminate and prevent a lot of slowdowns – that contributes increase of availability and reliability of machine works