The scientific studies on drug delivery systems that transport drugs to the targeted tissues, at a certain rate and desired time intervals, have gained popularity. The main goal of the drug delivery and release systems is to maintain the drug level in the blood plasma by balancing the amount of active ingredient. In this study, pH and temperature sensitive drug carriers were prepared using chitosan as a biopolymer and clay as a natural material. The characterization of the prepared materials was performed for structural analysis by FT-IR and for morphological analysis by SEM instruments. The swelling properties of the prepared materials were investigated. In this work, Ranitidine-HCl was used as a model drug. The prepared drug carriers were first loaded with Ranitidine-HCl and release properties of the materials were investigated at two different temperatures (25oC, 37oC) and various pH medium. The data obtained from the experiments indicated that the maximum release of Ranitidine–HCl from the prepared sample was observed at pH=7,6 buffer solution at both temperatures by comparing buffer solutions. It has been shown that the materials prepared in this study are suitable carriers for the Ranitidine-HCl drug active ingredient.

Mikroporozni elastomeri predstavljaju prostorno umrežene makromolekule sa izraženom ćelijskom strukturom. Količine izabranih komponenti umrežavajuće smese određuju eksploataciona svojstva ovih materijala. Za specifične primene elastomera neophodno je ostvariti željeni nivo umreženja kao i gustinu materijala. U ovom radu ispitan je uticaj sadržaja sredstva za ekspandiranje na svojstva mikroporoznih materijala na osnovu terpolimera poli-(etilen-ko-propilen-ko-2-etiliden-5-norbornen) kaučuka (EPDM)umreženih sumporom i ojačanih česticama čađi. Variran je sadržaj sredstva za ekspandiranje (1,3; 1,8 i 2,0 phr). Ustanovljeno je da su dobijeni elastomerni materijali pogodni za primenu u oblasti proizvodnje zaptivnih profila za potrebe automobilske industrije.

The substantial advantage of 3D printing is the ability to fabricate complex shapes objects from liquid molecules or powder grains which joins or solidifies using computer design files (CAD) to produce a three-dimensional object with material being added together layer by layer. This process is considered as an industrial technology. The most-commonly used 3D printing procedure is a material extrusion technique called fused deposition modelling. The producers of 3D printers have already developed prototypes for education purposes. The importance of the incorporation this printing method in schools is the fact. The learning experience for digital media is becoming a priority in school education. The practical application of this technique can be incorporated into a wide variety of school subjects to simplify the sophisticated theoretical concepts. 3D printing is the example of cooperation within material science and mathematics but this platform is very often not supported by the high school curriculum, but latest trends propose different approaches and make education close to the science achievements and contemporary life. Building lessons plans and project could help students to learn more contemporary achievement in this field. It is new trend to support enthusiastic teachers who want to implement this method of additive manufacturing in education. This paper provides an overview of 3D printing methods and highlights the possibility of their implementation in educational techniques.